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LIQUIFER Systems Group Gmbh

Obere Donaustraße 97/1/62

1020 Vienna / Austria

T +43 1 21885 - 05

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SynBio4Flav

Using knowledge gained in project Living Architecture on the use of Synthetic Microbial Consortia to perform targeted tasks, LIQUIFER Systems Group will develop ceramic membranes for use in the bioreactor developed in the project SynBio4Flav.

Date
January 2019 – December 2022

EU-H2020, Industrial Leadership grant for R&D activities in the field of Biotechnology

Consortium
The Spanish National Research Council (coordinator), Spain
Chalmers University of Technology, Sweden
German Institute of Human Nutrition, Germany
Wrocław University of Environmental and Life Sciences, Poland
University of Greifswald, Germany
University of Oviedo, Spain
Extrasynthese SAS, France
Biopolis SL, Spain
Explora SRL, Italy
Symrise AG, Germany 
LIQUIFER Systems Group GmbH, Austria

LSG team
Waltraut Hoheneder, Barbara Imhof, René Waclavicek, Molly Hogle

In this project aimed at providing a cost-effective alternative to current flavonoid production technology, LIQUIFER Systems Group steps further into gaining knowledge and expertise in the fascinating realm of synthetic biology.
SynBio4Flav’s ultimate goal is to deliver a paradigm shift in the procurement of flavonoids, or phytonutrients, that occur naturally in plants, each with its unique set of health benefits. Flavonoids are an integral part of the human diet and can be used in a wide range of industrial applications including the food & beverage industry, the pharmaceutical, nutraceutical, cosmetics, and materials industries, and in animal feed. Depending on the type, they can exhibit anti-oxidative, anti-inflammatory, anti-mutagenic, and anti-carcinogenic properties. They also support our immune and cardiovascular systems and help to modulate key functions of enzymes in our cells.
Thus far, small amounts of flavonoids are procured through a tedious process requiring an enormous amount of space to store plant-based biomass, and energy to transport it, treat, extract, and purify it. SynBio4Flav’s scientific challenge is to produce flavonoids in a laboratory context by breaking down their complex biosynthetic pathways into standardized specific parts, which can then be transferred to engineered microorganisms within Synthetic Microbial Consortia (SMC) to promote flavonoid assembly through distributed catalysis.
In addition, LSG will serve as mediator between the applications of synthetic biology and public perception. Events will be coordinated for public discourse encouraging exchange between various opinions amongst scientists, artists, philosophers and other experts.